Current status

The presumed mode of HIV acquisition of patients currently followed is depicted according to gender in Figure 12 (males) and Figure 13 (females), as well as by clinical centre in Figure 14. The majority of persons active in the SHCS acquired infection sexually (at least 80%).

Figure 15 illustrates the increasing use of multiple (i.e. triple or more than 3 drugs) combinations therapies in the SHCS. The proportion of non-treated patients has continuously decreased in the last few years and amounts, currently, to 3.2%.


Figure 12: Distribution of male patients actively followed in the SHCS in 2016, by presumed mode of HIV infection


Figure 13: Distribution of female patients actively followed in the SHCS in 2016, by presumed mode of HIV infection


Figure 14: Distribution of patients actively followed in the SHCS in 2016, by recruitment center and presumed mode of HIV infection

Figure 15: Trends in use of antiretroviral therapy in the SHCS, 1992 - 2016

As of December 2016, more than 91% of the patients were receiving at least three drugs (Figure 16).

Figure 17 depicts the situation of treatment status according to the CD4 cell count and by presumed mode of HIV acquisition. The proportion of patients with CD4 value below 350 cells/mm3 who have never been treated is small in all risk groups (<1%).>


Figure 16: Prescription of antiretroviral drug combinations to SHCS participants in 2016

Figure 17: Treatment status by presumed mode of HIV infection in the SHCS as of July 2016

Figure 18 summarizes the complex history of antiretroviral prescriptions in the SHCS.

In the last twenty years, the age structure of the cohort has drastically changed as depicted by Figure 19.


Figure 18: Cumulated number of antiretroviral prescriptions in the SHCS, 1992 - 2016

Figure 19: Age distribution of active patients by year in the SHCS, 1992 - 2016

The coverage proportion of the SHCS regarding HIV infected patients living in Switzerland is illustrated in Figure 20. We compared the number of patients ever registered in the SHCS with the number of confirmed positive HIV-tests reported by the Federal Office of Public Health (FOPH), as well as the number of patients with a documented AIDS diagnosis in the SHCS with the number of AIDS cases reported by the physicians to the FOPH. We see that compared to HIV infected patients, AIDS patients are better represented in the SHCS.

 

download
all figures