Current status


The presumed mode of HIV acquisition of patients currently followed is depicted according to gender in fig. 12 (males) and fig. 13 (females), as well as by clinical centre in fig. 14. The majority of persons active in the SHCS acquired infection sexually (about 85%).


fig. 12: Distribution of male patients actively followed in the SHCS in 2020, by presumed mode of HIV infection


fig. 13: Distribution of female patients actively followed in the SHCS in 2020, by presumed mode of HIV infection



fig. 14: Distribution of patients actively followed in the SHCS in 2020, by recruitment center and presumed mode of HIV infection

Figure 15 illustrates the increasing use of multiple (i.e. triple or more than 3 drugs) combinations therapies in the SHCS. The proportion of non-treated patients has continuously decreased in the last few years and amounts, currently, to less than 1%.


fig. 15: Trends in use of antiretroviral therapy in the SHCS, 1992 - 2020

 

As of December 2020, more than 90% of the patients were receiving at least three drugs (fig. 16).


fig. 16: Prescription of antiretroviral drug combinations to SHCS participants in 2020

 

Figure 17 depicts the situation of treatment status according to the CD4 cell count and by presumed mode of HIV acquisition. The proportion of patients with CD4 value below 350 cells/mm3 who have never been treated is small in all risk groups (<1%).


fig. 17: Treatment status by presumed mode of HIV infection in the SHCS as of July 2020

 

Figure 18 summarizes the complex history of antiretroviral prescriptions in the SHCS.

fig. 18: Cumulated number of antiretroviral prescriptions in the SHCS, 1992 - 2020

 

In the last twenty years, the age structure of the cohort has drastically changed as depicted by fig. 19.

fig. 19: Age distribution of active patients by year in the SHCS, 1992 - 2020

 

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