Current status
The presumed mode of HIV acquisition of patients currently followed is depicted according to gender in fig. 12 (males) and fig. 13 (females), as well as by clinical centre in fig. 14. The majority of persons active in the SHCS acquired infection sexually (about 85%).
fig. 12: Distribution of male patients actively followed in the SHCS in 2021, by presumed mode of HIV infection
fig. 13: Distribution of female patients actively followed in the SHCS in 2021, by presumed mode of HIV infection
fig. 14: Distribution of patients actively followed in the SHCS in 2021, by recruitment center and presumed mode of HIV infection
Figures 15 and 16 illustrate the increasing use of multiple (i.e. triple or more than 3 drugs) combinations therapies in the SHCS with an increase of dual therapy since 2016. The proportion of non-treated patients has continuously decreased in the last few years and amounts, currently, to less than 1%.
fig. 15: Trends in use of antiretroviral therapy in the SHCS, 1992 - 2021
fig. 16: Prescription of antiretroviral drug combinations to SHCS participants in 2021
Figure 17 depicts the situation of treatment status by presumed mode of HIV acquisition. The proportion of patients who have never been treated is small in all risk groups (<1%).
fig. 17: Treatment status by presumed mode of HIV infection in the SHCS as of July 2021
Figure 18 summarizes the complex history of antiretroviral prescriptions in the SHCS.
fig. 18: Cumulated number of antiretroviral prescriptions in the SHCS, 1992 - 2021
In the last twenty years, the age structure of the cohort has drastically changed as depicted by fig. 19.